MAINTENANCE. – Inserm handed to his Matignon Map Genomic Medicine, which provides for the creation of twelve genome sequencing centers
The gene medicine takes a hit accelerator in France. The health minister said Wednesday the microphone of Radio Classique opening 12 genomic high-throughput sequencing centers. A report was presented to Matignon, who declined several proposals to make the Hexagon a leading genomic medicine countries by 2025, with other nations sides already engaged in the sector.
first three platforms should thus be created by the end of the year. They will aim to achieve genome sequencing, especially for patients who do not have, at present, the necessary authorizations for the operation.
Personalized Medicine
In fact, gene sequencing reports to a very limited framework; it is reserved for people with cancer or rare diseases, and can detect the presence of a disease gene in the adult, the child, the fetus, or embryo (pre-implantation screening) .
the aim of this sequencing is to identify factors that could affect this gene to the disease, but also to anticipate the response to treatment. It is thus to develop personalized medicine, closer to the specifics of each individual. Another indication of genome sequencing concerning paternity tests.
Common Diseases
The government wants to extend this framework to that of patients with less rare diseases (diabetes, obesity …) can benefit from genomic sequencing. The report’s objective is to achieve sequencing 235,000 per year; 20,000 patients with rare diseases and their families could benefit by 2020. In addition, a priority target of 50,000 patients (with metastatic cancers refractory) was determined.
The objective of this Plan is therefore to “integrate genomic medicine in the course of care and care for common diseases,” say the authors. The challenge is to reduce the cost of genome sequencing – now, the operation costs between 1500 and 1800 euros
The French delay
the Plan is also intended to raise France among the great nations of genomic sequencing, while the country has a notorious delay in the field. “The question is how this plan will be implemented, said Professor Philippe Amouyel, an epidemiologist at the University Hospital of Lille, told the reporters. Countries like the United Kingdom, Canada and the United States began there more than five years and have invested heavily in the sector. We need to strengthen our culture of genomic sequencing. “
In this case, the Plan provides up to € 670 million over five years, from both the public and private . These resources will fund the sequencing platforms, but also a national center for supercomputing with the task of analyzing all the data -. But also to protect
Because this is where one of the major challenges. “There are three and a half billion to interpret information for whole genome sequencing. We need software tailored to these approaches. Currently, most of these programs come from the United States. ” On the horizon, so many “business booming” and the growth of a promising industry.
“Genetics for Dad”
This breakthrough in French field of genomic medicine was hailed by industry experts. This is the case of Dr. Lawrence Alexander, president of INA Vision. “It’s a good thing that the state understands that the genetic father is dead and must pass DNA sequencing,” he says … keeping all proportions. In fact, this plan will take time to compete with US giants, Canadian or Dutch, already well established in this emerging field of contemporary medicine.
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