Sunday, March 15, 2015

Cortex repair with graft neurons – Linformatique.org

A successful repair mouse brain by a neural transplant was performed by scientists. The fight against neurodegenerative infections, this feat could be experienced.

Revert changes of the cerebral organs, an impossible performance? Not quite. A group of scientists from the Institute for Interdisciplinary Research in Human Biology and Molecular Brussels and INSERM led to transplantation of neurons in the damaged cortex of experimental mice. Part of the damaged brain of these mice laboratories was actually repaired.

An automatic recovery

encouraging are the results of these experiments are published in Neuron, even if they were made with rodents. Researchers are based on an observation that shows that the parts of the brain trying to cure infected automatically, especially in case of injury. The idea was to trigger the self-healing activity.

To get there, it’s in vitro embryo stem cells were fabricated to give neurons, scientists have introduced into the cortex rodents. Movement, vision and hearing are controlled by this complex part of the brain, the cortex. There is no cure for damage of this part of the brain, except for a very long period of rehabilitation is particularly in cases of head trauma or stroke.

However, in a year of experience, in 60% of laboratory mice, neural transplantation was effective. Normal operation of the cortex, previously damaged resumed. These are clusters of undifferentiated cells and tumors that have appeared in other experimental mice.

Alzheimer’s, Parkinson

According to the researchers, it is to a “global performance” that would have a positive influence on the studies of neurodegenerative disorders, including Alzheimer’s and Parkinson’s. However, no assurance imminent attempt in humans, given the complexity of their brains Advanced. The model will be implemented in monkeys whose brain is the same man. This is why patience is required for one day repair brain damage made by humans transplant neurons.

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